Article
Evidence for CYP2D6 expression in human lung.
Biochemical and biophysical research communications - 8 Dec 1997
Guidice J M, Marez D, Sabbagh N, Legrand-Andreoletti M, Spire C, Alcaïde E, Lafitte J J, Broly F
Abstract excerpt
The cytochrome P450 CYP2D6 gene (CYP2D6) expression was examined in samples from human bronchial mucosa and lung parenchyma using reverse transcription-polymerase chain reaction (RT-PCR) and immunochemistry. Except specimen from a patient previously genotyped as homozygous for a complete deletion of the gene, all tissue samples were positive. When compared to that in the liver, the mean level of CYP2D6 mRNA was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
