Article
Genetic polymorphism of CYP2D6 and lung cancer risk in African-Americans and Caucasians in Los Angeles County.
Carcinogenesis - 1 Jun 1997
London S J, Daly A K, Leathart J B, Navidi W C, Carpenter C C, Idle J R
Abstract excerpt
The well described genetic polymorphism of the CYP2D6 gene influences response to a wide variety of therapeutic agents metabolized by the CYP2D6 enzyme product. CYP2D6 also appears to play a role, along with other cytochrome P450 enzymes, in the metabolic activation of the tobacco specific nitros...
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