Article
Genotyping of the CYP2D6 gene in Norwegian lung cancer patients and controls.
Pharmacogenetics - 1 Apr 1994
Tefre T, Daly A K, Armstrong M, Leathart J B, Idle J R, Brøgger A, Børresen A L
Abstract excerpt
Genotyping of five CYP2D6 alleles (wt, A,B,D,E) has been performed in 218 lung cancer patients and 289 healthy controls. PCR-methods were used to determine the CYP2D6A and CYP2D6B alleles. Both patients and controls were of Caucasian Norwegian origin. In the lung cancer group all major histological types were represented. The frequency of the CYP2D6B allele which is associated with poor metabolizers (PM), was...
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