Article
Genotyping of the CYP2D6 gene in Norwegian lung cancer patients and controls.
Pharmacogenetics - 1 Apr 1994
Tefre T, Daly A K, Armstrong M, Leathart J B, Idle J R, Brøgger A, Børresen A L
Abstract excerpt
Genotyping of five CYP2D6 alleles (wt, A,B,D,E) has been performed in 218 lung cancer patients and 289 healthy controls. PCR-methods were used to determine the CYP2D6A and CYP2D6B alleles. Both patients and controls were of Caucasian Norwegian origin. In the lung cancer group all major histologic...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Base Sequence
- Carcinoma
- Chi-Square Distribution
- Cytochrome P-450 CYP2D6
- Cytochrome P-450 Enzyme System
- Disease Susceptibility
- Female
- Genetic Markers
- Genetic Variation
- Genotype
- Humans
- Lung
- Lung Neoplasms
- Male
