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Article

Xenobiotic metabolism in differentiated human bronchial epithelial cells

13 Oct 2016

Abstract excerpt

Differentiated human bronchial epithelial cells in air liquid interface cultures (ALI-PBEC) represent a promising alternative for inhalation studies with rodents as these 3D airway epithelial tissue cultures recapitulate the human airway in multiple aspects, including morphology, cell type composition, gene expression and xenobiotic metabolism. We performed a detailed longitudinal gene expression analysis during...

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PMID: 27738743
DOI: 10.1007/s00204-016-1868-7

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