Article
Hepatic CYP2B6 is altered by genetic, physiologic, and environmental factors but plays little role in nicotine metabolism.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Jun 2010
Al Koudsi N, Tyndale R F
Abstract excerpt
Human cytochrome P4502B6 (CYP2B6) is predominantly expressed in the liver and it plays a major role in the metabolism of several therapeutically important drugs and environmental toxicants. The objective was twofold: (1) to determine the role of genetic, physiological, and environmental factors i...
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