Article
Comparisons of CYP2D messenger RNA splice variant profiles in human lung tumors and normal tissues.
Cancer research - 1 Jul 1997
Huang Z, Fasco M J, Spivack S, Kaminsky L S
Abstract excerpt
Allelic variants of the CYP2D6 gene, a member of the cytochrome P450 gene superfamily, have been implicated in susceptibility to lung carcinogenesis. Human breast CYP2D6 and CYP2D7P (from a pseudogene) mRNAs were previously reported to be expressed as a series of splice variants. In this study, the expression of full-length and splice variants of these mRNAs in human lung tissue and tumors are reported for the...
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