Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Leishmania major infection in C57BL/10 mice differing at the Lps locus: a new non-healing phenotype.

Medical microbiology and immunology - 1 Oct 1997

Müller I, Freudenberg M, Kropf P, Kiderlen A F, Galanos C

Abstract excerpt

The course of cutaneous leishmaniasis was examined in mice from two genetically closely related strains, C57BL/10ScCr (Cr) and C57BL/10ScSn (Sn). Sn mice are able to heal Leishmania major infections, while Cr mice are unable to heal. The cutaneous lesions of the Cr mice progressed continuously and the increase in lesion size was paralleled by an unrestricted growth of the parasites in vivo. Cr mice, in contrast...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to In Vitro Techniques
Share to Interferon-gamma
Share to Lipopolysaccharides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Phenotype

Share to Species Specificity

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 9403834
DOI: 10.1007/s004300050048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Leishmania major infection in C57BL/10 mice differing at the Lps locus: a new non-healing phenotype.PMID 9403834Read ↗

Infection of C57BL/10ScCr and C57BL/10ScNCr mice withLeishmania majorreveals a role for Toll-like receptor 4 in the control of parasite replicationSemantic proximity Read ↗

Limits of a deletion spanning Tlr4 in C57BL/10ScCr miceSemantic proximity Read ↗

Mice unresponsive to GM-CSF are unexpectedly resistant to cutaneous Leishmania major infection.Semantic proximity Read ↗

Genetic background influences immune responses and disease outcome of cutaneous L. mexicana infection in mice.Semantic proximity Read ↗

Rapidly fatal leishmaniasis in resistant C57BL/6 mice lacking TNF.Semantic proximity Read ↗

iNOS-producing inflammatory dendritic cells constitute the major infected cell type during the chronic Leishmania major infection phase of C57BL/6 resistant mice.Semantic proximity Read ↗

Wound healing response is a major contributor to the severity of cutaneous leishmaniasis in the ear model of infectionSemantic proximity Read ↗

A locus on chromosome 9 is associated with differential response of 129S1/SvImJ and FVB/NJ strains of mice to systemic LPS.Semantic proximity Read ↗

An essential role for IL-13 in maintaining a non-healing response following Leishmania mexicana infectionSemantic proximity Read ↗

PKCδ regulates IL-12p40/p70 production by macrophages and dendritic cells, driving a type 1 healer phenotype in cutaneous leishmaniasis.Semantic proximity Read ↗

Genes other than TLR4 are involved in the response to inhaled LPS.Semantic proximity Read ↗

Up-regulation of T helper 2 and down-regulation of T helper 1 cytokines during murine retrovirus-induced immunodeficiency syndrome enhances susceptibility of a resistant mouse strain to Leishmania amazonensis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.