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Article

A locus on chromosome 9 is associated with differential response of 129S1/SvImJ and FVB/NJ strains of mice to systemic LPS.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2011

Yang Ivana V, Rutledge Holly R, Yang Jun, Warg Laura A, Sevilla Sergio D, Schwartz David A

Abstract excerpt

Although polymorphisms in TLR receptors and downstream signaling molecules affect the innate immune response, these variants account for only a portion of the ability of the host to respond to microorganisms. To identify novel genes that regulate the host response to systemic lipopolysaccharide (LPS), we created an F2 intercross between susceptible (FVB/NJ) and resistant (129S1/SvImJ) strains, challenged F2...

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Identifiers

PMID: 21720866
DOI: 10.1007/s00335-011-9340-8
PMCID: PMC4157901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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