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Article

Genetic background influences immune responses and disease outcome of cutaneous L. mexicana infection in mice.

International immunology - 1 Oct 2005

Rosas Lucia E, Keiser Tracy, Barbi Joseph, Satoskar Anjali A, Septer Alecia, Kaczmarek Jennifer, Lezama-Davila Claudio M, Satoskar Abhay R

Abstract excerpt

The experimental model of high-dose Leishmania mexicana infection is used frequently to study molecular mechanisms regulating Th2 response since most inbred mice regardless of their genetic background display Th2 cytokine-dependent susceptibility to L. mexicana unlike Leishmania major. Here, we analyzed the course of L. mexicana infection in BALB/c, C57BL/6 and CBA/J mouse strains using low-dose ear infection...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16141242
DOI: 10.1093/intimm/dxh313

Genes

STAT6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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