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Article

Limits of a deletion spanning Tlr4 in C57BL/10ScCr mice

1 Feb 2000

Abstract excerpt

Proceeding from our observation that LPS-unresponsive mice of the strain C57BL/10ScCr mice fail to express the Tlr4 gene [Poltorak A, He X. Smirnova I et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998; 282: 2085], we have defined the exact limits of a deletion encompassing Tlr4 in the C57BL/10ScCr genome. The deletion removes 74723 bp of DNA, with reference to...

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PMID: 11061032
DOI: 10.1177/09680519000060010701

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