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Article

An essential role for IL-13 in maintaining a non-healing response following Leishmania mexicana infection

1 Oct 2002

Abstract excerpt

A comparison of the growth of Leishmania mexicana in IL-4(-/-), IL-4Ralpha(-/-) and wild-type BALB/c mice demonstrated a disease exacerbative role for IL-13 as well as IL-4. Thus, while both IL-4(-/-) and IL-4Ralpha(-/-) mice were more resistant than wild-type controls to infection with L. mexicana, IL-4Ralpha(-/-) mice, which are unresponsive to IL-13 as well as IL-4, were significantly more resistant to...

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Identifiers

PMID: 12355446
DOI: 10.1002/1521-4141(2002010)32:10<2923::aid-immu2923>3.0.co;2-e

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