Heterogeneity and common features of defective hepatitis B virus genomes derived from spliced pregenomic RNA.

doi:10.1006/viro.1997.8863

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Article

Heterogeneity and common features of defective hepatitis B virus genomes derived from spliced pregenomic RNA.

Virology - 24 Nov 1997

Günther S, Sommer G, Iwanska A, Will H

Abstract excerpt

Defective hepatitis B virus (HBV) genomes derived from packaging and reverse transcription of spliced RNA pregenomes were reported to be associated with progression to chronic infection. Since only two types with similarly spliced regions were characterized so far we reasoned that additional "spl...

Topics

Cloning, Molecular
Defective Viruses
Genetic Variation
Genome, Viral
Hepatitis B
Hepatitis B Core Antigens
Hepatitis B virus
Humans
Polymerase Chain Reaction
RNA Precursors
RNA Splicing
RNA, Viral
Trans-Activators
Viral Regulatory and Accessory Proteins

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