Article
Genotype-specific synthesis and secretion of spliced hepatitis B virus genomes in hepatoma cells.
Virology - 5 Jun 2000
Sommer G, van Bömmel F, Will H
Abstract excerpt
Hepatitis B virus-infected patients frequently have viral particles with DNA derived from differently spliced RNA. Which factors influence the synthesis of these splice variants is unclear. We analysed the type of splice variants produced from different genotypes and determined whether they are secreted as efficiently as wild-type virus. We demonstrate production of a single splice variant from genotypes D, C,...
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