Article
Quantitative analysis of the splice variants expressed by the major hepatitis B virus genotypes.
Microbial genomics - 1 Jan 2021
Lim Chun Shen, Sozzi Vitina, Littlejohn Margaret, Yuen Lilly K W, Warner Nadia, Betz-Stablein Brigid, Luciani Fabio, Revill Peter A, Brown Chris M
Abstract excerpt
Hepatitis B virus (HBV) is a major human pathogen that causes liver diseases. The main HBV RNAs are unspliced transcripts that encode the key viral proteins. Recent studies have shown that some of the HBV spliced transcript isoforms are predictive of liver cancer, yet the roles of these spliced transcripts remain elusive. Furthermore, there are nine major HBV genotypes common in different regions of the world,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.