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Article

Secreted hepatitis B virus splice variants differ by HBV genotype and across phases of chronic hepatitis B infection.

Journal of viral hepatitis - 1 Aug 2022

Maslac Olivia, Wagner Josef, Sozzi Vitina, Mason Hugh, Svarovskaia Jenny, Tan Susanna, Gaggar Anuj, Locarnini Stephen, Yuen Lilly, Littlejohn Margaret, Revill Peter A

Abstract excerpt

Chronic hepatitis B (CHB) is characterized by progression through different phases of hepatitis B virus (HBV) infection and disease. Although not necessary for HBV replication, there is increasing evidence that HBV splice variants are associated with liver disease progression and pathogenesis. However, there have been no studies till date on the frequency or diversity of splice variants for different HBV...

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Identifiers

PMID: 35582878
DOI: 10.1111/jvh.13702
PMCID: PMC9544302

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