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One single nucleotide difference alters the differential expression of spliced RNAs between HBV genotypes A and D.

Virus research - 1 Jun 2013

Huang Chien-Chiao, Kuo Tzer-Min, Yeh Chau-Ting, Hu Cheng-Po, Chen Ya-Ling, Tsai Yue-Lin, Chen Mong-Liang, Chou Yu-Chi, Chang Chungming

Abstract excerpt

Hepatitis B virus (HBV) is generally classified into eight genotypes (A to H) based on genomic sequence divergence. The sequence variation among the different HBV genotypes suggests that the spliced RNAs should be different from genotype to genotype. However, the cis-acting element involved in the modulation of the distinct expression profiles of spliced HBV RNAs remains unidentified. Moreover, the biological...

Topics

Cell Line
Genotype
Hepatitis B virus
Hepatocytes
Humans
Polymorphism, Single Nucleotide
RNA Splicing
RNA, Messenger
RNA, Viral

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23501362
DOI: 10.1016/j.virusres.2013.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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