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A standardized assay for the quantitative detection of serum HBV RNA in chronic hepatitis B patients

28 Feb 2022

Abstract excerpt

Serum hepatitis B virus (HBV) pregenomic RNA (pgRNA) is a surrogate marker for reflecting the transcriptional activity of covalently closed circular DNA. However, there is still no standardized assay for the quantitative detection of serum HBV RNA in chronic hepatitis B patients. In this study, quantitative polymerase chain reactions for detecting the preC/C-RNA (preC/C region HBV pgRNA), SF-RNA (splicing...

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PMID: 35220917
DOI: 10.1080/22221751.2022.2045874

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