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Article

Leptin sensitivity in nonobese glucagon-like peptide I receptor -/- mice.

Diabetes - 1 Dec 1997

Scrocchi L A, Brown T J, Drucker D J

Abstract excerpt

Glucagon-like peptide I (GLP-I) stimulates glucose-dependent insulin secretion and inhibits food intake in the central nervous system. Because leptin reduces food intake but inhibits insulin secretion, we examined leptin action in mice with a null mutation in the GLP-I receptor. Intracerebroventricular leptin administration inhibited food intake in both wild-type and GLP-I receptor (GLP-IR) -/- mice, and daily...

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Identifiers

PMID: 9392491
DOI: 10.2337/diab.46.12.2029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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