Article
Association between p53 mutation and clinicopathological features of non-small cell lung cancer.
Japanese journal of clinical oncology - 1 Aug 1997
Guang S G, Ogura T, Sekine I, Yokozaki M, Esumi H, Kodama T, Nagai K
Abstract excerpt
Genetic alterations in exons 5-8 of the p53 gene, determined by single-strand conformation polymorphism and sequencing analyses, and the clinicopathological characteristics of 108 patients with non-small cell lung cancer were compared. Mutations in this gene were found in 37 of the 108 patients (...
Topics
- Adenocarcinoma
- Adenocarcinoma, Papillary
- Adult
- Aged
- Aged, 80 and over
- Analysis of Variance
- Base Sequence
- Carcinoma, Adenosquamous
- Carcinoma, Large Cell
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Cell Nucleus
- Cytosine
- DNA, Neoplasm
- Disease-Free Survival
- Epithelium
- Exons
- Female