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Article

Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer.

Journal of the National Cancer Institute - 15 Dec 1993

Mitsudomi T, Oyama T, Kusano T, Osaki T, Nakanishi R, Shirakusa T

Abstract excerpt

BACKGROUND: Inactivation of the p53 tumor suppressor gene (also known as TP53) through a point mutation and/or loss of heterozygosity is one of the most common genetic changes found in various types of human tumors. PURPOSE: Our purpose was to investigate the relationship between the presence of p53 gene mutations and survival of patients with non-small-cell lung cancer (NSCLC) of all stages who underwent surgery...

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Identifiers

PMID: 8246288
DOI: 10.1093/jnci/85.24.2018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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