Article
Association of p53 gene mutation and telomerase activity in resectable non-small cell lung cancer.
Chest - 1 Aug 2001
Maniwa Y, Yoshimura M, Obayashi C, Inaba M, Kiyooka K, Kanki M, Okita Y
Abstract excerpt
PURPOSE: Mutation of the p53 gene and deregulation of telomerase may be essential for canceration in some malignant diseases. However, relationships between these occurrences have not yet been clarified. We examined the roles of p53 gene mutation and telomerase activity relative to the clinical and pathologic features of non-small cell lung carcinoma (NSCLC). METHODS: Frozen sections of 40 surgically resected...
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