Article
Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions.
Molecular and cellular biology - 1 Dec 1997
Fernandes L, Rodrigues-Pousada C, Struhl K
Abstract excerpt
Saccharomyces cerevisiae contains eight members of a novel and fungus-specific family of bZIP proteins that is defined by four atypical residues on the DNA-binding surface. Two of these proteins, Yap1 and Yap2, are transcriptional activators involved in pleiotropic drug resistance. Although initially described as AP-1 factors, at least four Yap proteins bind most efficiently to TTACTAA, a sequence that differs at...
Topics
- Amino Acid Sequence
- Base Sequence
- Basic-Leucine Zipper Transcription Factors
- Binding Sites
- Cyclic AMP-Dependent Protein Kinases
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- G-Box Binding Factors
- Genes, Fungal
- Molecular Sequence Data
- Multigene Family
- Phenotype
- Saccharomyces cerevisiae