Article
Transcriptional activation mediated by the yeast AP-1 protein is required for normal cadmium tolerance.
The Journal of biological chemistry - 20 May 1994
Wemmie J A, Wu A L, Harshman K D, Parker C S, Moye-Rowley W S
Abstract excerpt
The yeast YAP1 gene encodes a transcriptional regulatory protein that utilizes a basic region-leucine zipper (bZip) DNA-binding domain to recognize its cognate DNA element. A synthetic reporter gene containing a SV40 AP-1 response element (ARE) cloned upstream of a TRP5 promoter-lacZ gene fusion...
Topics
- Base Sequence
- Blotting, Western
- Cadmium
- Cycloheximide
- DNA Primers
- DNA-Binding Proteins
- Drug Resistance, Microbial
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Molecular Sequence Data
- Mutagenesis
- Phenotype
- Plasmids
- Recombinant Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Deletion