Article
Diazaborine resistance in the yeast Saccharomyces cerevisiae reveals a link between YAP1 and the pleiotropic drug resistance genes PDR1 and PDR3.
The Journal of biological chemistry - 24 Oct 1997
Wendler F, Bergler H, Prutej K, Jungwirth H, Zisser G, Kuchler K, Högenauer G
Abstract excerpt
We have investigated the mechanisms underlying resistance to the drug diazaborine in Saccharomyces cerevisiae. We used UV mutagenesis to generate resistant mutants, which were divided into three different complementation groups. The resistant phenotype in these groups was found to be caused by al...
Topics
- Amino Acid Sequence
- Antifungal Agents
- Boron Compounds
- Cycloheximide
- DNA-Binding Proteins
- Drug Resistance, Microbial
- Fungal Proteins
- Genes, Fungal
- Genomic Library
- Genotype
- Molecular Sequence Data
- Mutagenesis
- Phenanthrolines
- Saccharomyces cerevisiae