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Article

Yeast bZip proteins mediate pleiotropic drug and metal resistance.

The Journal of biological chemistry - 5 Sept 1993

Wu A, Wemmie J A, Edgington N P, Goebl M, Guevara J L, Moye-Rowley W S

Abstract excerpt

Saccharomyces cerevisiae contains a group of transcription factors related to mammalian c-Jun. This yeast Jun-family of proteins consists of GCN4, a regulator of genes involved in amino acid biosynthesis, and yAP-1, a factor conferring pleiotropic drug resistance when overexpressed. In the work described here, we show that a third member of the yeast Jun-family exists. This protein has been designated CAD1 and...

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Identifiers

PMID: 8360174

Genes

YAP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Yeast bZip proteins mediate pleiotropic drug and metal resistance.PMID 8360174Read ↗

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Yap1: a DNA damage responder in Saccharomyces cerevisiae.Semantic proximity Read ↗

Clustered amino acid substitutions in the yeast transcription regulator Pdr3p increase pleiotropic drug resistance and identify a new central regulatory domain.Semantic proximity Read ↗

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