Article
The nuclear actin-related protein Act3p/Arp4p of Saccharomyces cerevisiae is involved in transcription regulation of stress genes.
Molecular microbiology - 1 Nov 2003
Görzer Irene, Schüller Christoph, Heidenreich Erich, Krupanska Ludmila, Kuchler Karl, Wintersberger Ulrike
Abstract excerpt
A mutational analysis of the essential nuclear actin-related protein of Saccharomyces cerevisiae, Act3p/Arp4p, was performed. The five residues chosen for substitution were amino acids conserved between actin and Act3p/Arp4p, the tertiary structure of which most probably resembles that of actin. Two thermosensitive (ts) mutants, a single and a double point mutant, and one lethal double point mutant were obtained....
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