Article
Analysis of the oxidative stress regulation of the Candida albicans transcription factor, Cap1p.
Molecular microbiology - 1 May 2000
Zhang X, De Micheli M, Coleman S T, Sanglard D, Moye-Rowley W S
Abstract excerpt
CAP1 encodes a basic region-leucine zipper (bZip) transcriptional regulatory protein that is required for oxidative stress tolerance in Candida albicans. Cap1p is a homologue of a Saccharomyces cerevisiae bZip transcription factor designated Yap1p that is both required for oxidative stress tolerance and localized to the nucleus in response to the presence of oxidants. Oxidant-regulated localization of Yap1p to...
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