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Article

Yap1: a DNA damage responder in Saccharomyces cerevisiae.

Mechanisms of ageing and development - 1 Apr 2012

Rowe Lori A, Degtyareva Natalya, Doetsch Paul W

Abstract excerpt

Activation of signaling pathways in response to genotoxic stress is crucial for cells to properly repair DNA damage. In response to DNA damage, intracellular levels of reactive oxygen species increase. One important function of such a response could be to initiate signal transduction processes. We have employed the model eukaryote Saccharomyces cerevisiae to delineate DNA damage sensing mechanisms. We report a...

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Identifiers

PMID: 22433435
DOI: 10.1016/j.mad.2012.03.009
PMCID: PMC3351557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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