Article
Formation of one or more intrachain disulphide bonds is required for the intracellular processing and transport of CD36.
The Biochemical journal - 1 Dec 1997
Gruarin P, Sitia R, Alessio M
Abstract excerpt
In monocytes/macrophages, CD36 is thought to have a role as a scavenger receptor, mediating the phagocytosis of apoptotic cells and the endocytic uptake of oxidized low-density lipoproteins and fatty acids. The proposed topology of CD36 predicts that, of ten cysteine residues, six lie in the extracellular domain, whereas four are equally distributed in the two short terminal tails flanking the N-terminal and...
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