Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human CD36: Gene Regulation, Protein Function, and Its Role in Atherosclerosis Pathogenesis

13 Jun 2025

Abstract excerpt

Human CD36 plays an important role in ligand binding, signalling, cell adhesion, and the regulation of angiogenesis. As a scavenging receptor, it is responsible for clearing long-chain fatty acids (LCFAs) and removing approximately 50% of oxidised low-density lipoprotein (ox-LDL) from plasma. The CD36 gene is alternatively spliced. It has several alternative promoters and first exons. The alternative transcripts...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Lipoproteins and Cardiovascular Health
Share to Peroxisome Proliferator-Activated Receptors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40565598
DOI: 10.3390/genes16060705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human CD36: Gene Regulation, Protein Function, and Its Role in Atherosclerosis PathogenesisPMID 40565598Read ↗

Molecular basis of human CD36 gene mutations.Semantic proximity Read ↗

Soluble CD36- a marker of the (pathophysiological) role of CD36 in the metabolic syndrome?Semantic proximity Read ↗

The role of CD36 in cardiovascular disease.Semantic proximity Read ↗

Alternative promoter usage of the membrane glycoprotein CD36Semantic proximity Read ↗

The macrophage Ox-LDL receptor, CD36 and its association with type II diabetes mellitus.Semantic proximity Read ↗

A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians.Semantic proximity Read ↗

Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile.Semantic proximity Read ↗

Variants of CD36 gene and their association with CD36 protein expression in platelets.Semantic proximity Read ↗

CD36 gene is associated with thickness of atheromatous plaque and ankle-brachial index in patients with early coronary artery disease.Semantic proximity Read ↗

Is CD36 gene polymorphism in region encoding lipid-binding domain associated with early onset CAD?Semantic proximity Read ↗

Human CD36 deficiency is associated with elevation in low-density lipoprotein-cholesterol.Semantic proximity Read ↗

Pathophysiology of Human Genetic CD36 DeficiencySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.