Article
A carboxyl terminal truncation mutant of CD36 is secreted and binds thrombospondin: evidence for a single transmembrane domain.
Blood - 15 Jul 1994
Pearce S F, Wu J, Silverstein R L
Abstract excerpt
CD36 has been implicated in several intracellular signalling events, including platelet and monocyte activation, and receptor-mediated internalization of bound ligands such as oxidized low-density lipoprotein and apoptotic neutrophils. These processes are presumably mediated by the intracytoplasmic domain(s) of the molecule. By analysis of hydrophobicity plots and by analogy to rat LIMPII, which has a 60%...
Topics
- Amino Acid Sequence
- Animals
- Antigens, CD
- CD36 Antigens
- CHO Cells
- Cell Membrane
- Cricetinae
- Humans
- Membrane Glycoproteins
- Molecular Sequence Data
- Mutation
- Thrombospondins