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Article

Frequent somatic mutations of the APC and p53 genes in sporadic ampullary carcinomas.

Japanese journal of cancer research : Gann - 1 Sept 1997

Imai Y, Oda H, Tsurutani N, Nakatsuru Y, Inoue T, Ishikawa T

Abstract excerpt

Although a close relation of somatic mutations of the adenomatous polyposis coli gene with ampullary carcinomas in familial adenomatous polyposis patients has been reported, the possible association with sporadic ampullary neoplasms has not been fully examined. We have therefore investigated loss of heterozygosity at the adenomatous polyposis coli locus and the mutational status of a portion of the adenomatous...

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Identifiers

PMID: 9369932
DOI: 10.1111/j.1349-7006.1997.tb00460.x
PMCID: PMC5921514

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APC

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Source receipt: pubmed, retrieved 7 Sept 2026.

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