Article
Frequent somatic mutations of the APC and p53 genes in sporadic ampullary carcinomas.
Japanese journal of cancer research : Gann - 1 Sept 1997
Imai Y, Oda H, Tsurutani N, Nakatsuru Y, Inoue T, Ishikawa T
Abstract excerpt
Although a close relation of somatic mutations of the adenomatous polyposis coli gene with ampullary carcinomas in familial adenomatous polyposis patients has been reported, the possible association with sporadic ampullary neoplasms has not been fully examined. We have therefore investigated loss...
Topics
- Adenomatous Polyposis Coli
- Aged
- Aged, 80 and over
- Ampulla of Vater
- Common Bile Duct Neoplasms
- Duodenal Neoplasms
- Exons
- Female
- Genes, APC
- Genes, p53
- Humans
- Liver Neoplasms
- Lymphatic Metastasis
- Male
- Middle Aged
- Mutation
- Neoplasm Invasiveness
- Neoplasm Staging