Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

K-ras mutation in a tubular adenoma originating at an ileostomy in a familial adenomatous polyposis patient.

The American journal of gastroenterology - 1 Mar 1996

Herring J A, Hall C C, Johnson J A, Poole G V, Subramony C, Suvarna-Gurram V, Hall T J

Abstract excerpt

Genetic alterations in a tubular adenoma with severe dysplasia arising in a Brooke ileostomy of a familial adenomatous polyposis patient were analyzed. Clinical and morphological characteristics suggest that ileal mucosa progressed to colonic metaplasia and then to dysplastic adenoma. Such changes at ileostomy sites are rare, and little is known about the associated genetic alterations. To determine whether...

Topics

Adenoma
Adenomatous Polyposis Coli
Aged
Base Sequence
Genes, ras
Humans
Ileal Neoplasms
Ileostomy
Male
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Source

Identifiers

PMID: 8633516

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8633516-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

K-ras mutation in a tubular adenoma originating at an ileostomy in a familial adenomatous polyposis patient.PMID 8633516Read ↗

Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP).Semantic proximity Read ↗

Prevalence and morphology of pouch and ileal adenomas in familial adenomatous polyposis.Semantic proximity Read ↗

Somatic mutations of the adenomatous polyposis coli gene in gastroduodenal tumors from patients with familial adenomatous polyposis.Semantic proximity Read ↗

Genetic epidemiology of mutated K-ras proto-oncogene, altered suppressor genes, and microsatellite instability in colorectal adenomas.Semantic proximity Read ↗

K-ras gene mutations in adenomas and carcinomas of the colon.Semantic proximity Read ↗

Somatic mutations of the APC, KRAS, and TP53 genes in nonpolypoid colorectal adenomas.Semantic proximity Read ↗

Somatic APC and K-ras codon 12 mutations in periampullary adenomas and carcinomas from familial adenomatous polyposis patients.Semantic proximity Read ↗

Frequent somatic mutations of the APC and p53 genes in sporadic ampullary carcinomas.Semantic proximity Read ↗

K-ras mutation and loss of heterozygosity at 17p with beta-catenin accumulation in intramucosal carcinoma of the ileostomy in familial adenomatous polyposis: a case report.Semantic proximity Read ↗

Advanced gastroduodenal polyposis with ras mutations in a patient with familial adenomatous polyposis.Semantic proximity Read ↗

Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomasSemantic proximity Read ↗

APC and p53 mutations in de novo colorectal adenocarcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.