Article
[Apolipoprotein E gene polymorphisms and Alzheimer disease].
Yi chuan xue bao = Acta genetica Sinica - 1 Dec 2003
Chen Deng, Zhang Jun-Wu, Zhang Zhen-Xin, Zhao Hua-Lu, Li Xiao-Qing, Wu Ya-Ning, Qu Qiu-Ming
Abstract excerpt
PCR-RFLP was used to investigate the distribution differences of apolipoprotein E (APOE) alleles and genotypes between sporadic Alzheimer disease (AD) patients (n = 160) and healthy control individuals (n = 195) in Chinese Han population. The results showed that the allelic frequencies of APOE epsilon 2, epsilon 3 and epsilon 4 were 0.056, 0.713 and 0.231 in AD group respectively, and 0.082, 0.844 and 0.074 in...
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