Article
[Genetic association between the apolipoprotein E (ApoE) gene alleles and various forms of Alzheimer's disease].
Genetika - 1 Apr 2001
Korovaĭtseva G I, Shcherbatykh T V, Selezneva N V, Gavrilova S I, Golimbet V E, Voskresenskaia N I, Rogaev E I
Abstract excerpt
Allele epsilon 4 of the apolipoprotein E (APOE) gene is associated with higher risk of Alzheimer's disease (AD) in many, though not all, ethnic groups. The APOE allele and genotype frequency distributions were studied in 207 AD patients without cerebrovascular disorders, 62 AD patients with cerebrovascular disorders (combined AD), and 206 control individuals (ethnic Russians from the Russian population). The...
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