Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expanded CAG/CTG repeats in bipolar disorder: no correlation with phenotypic measures of illness severity.

Biological psychiatry - 15 Nov 1997

Craddock N, McKeon P, Moorhead S, Guy C, Harrison D, Mynett-Johnson L, Claffey E, Feldman E, McGuffin P, Owen M J, O'Donovan M C

Abstract excerpt

The hypothesis that expanded trinucleotide repeats (TNRs) contribute to the pathogenesis of bipolar disorder has received strong support from recent studies showing that, on average, bipolar patients carry larger repeat sequences of the TNR motif CAG/CTG than do controls. It has been postulated that intergenerational expansion of a TNR may be responsible for the tendency for age of onset to become earlier in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Severity of Illness Index

Share to Trinucleotide Repeats

Source

Identifiers

PMID: 9359972
DOI: 10.1016/S0006-3223(96)00516-1

Genes

TNR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expanded CAG/CTG repeats in bipolar disorder: no correlation with phenotypic measures of illness severity.PMID 9359972Read ↗

Exclusion of expansion of 50 CAG/CTG trinucleotide repeats in bipolar disorder.Semantic proximity Read ↗

Anticipation and repeat expansion in bipolar disorder.Semantic proximity Read ↗

Novel CAG/CTG repeat expansion mutations do not contribute to the genetic risk for most cases of bipolar disorder or schizophrenia.Semantic proximity Read ↗

Expanded trinucleotide CAG repeats in families with bipolar affective disorder.Semantic proximity Read ↗

Anticipation in bipolar affective disorder.Semantic proximity Read ↗

Anticipation in Swedish families with bipolar affective disorder.Semantic proximity Read ↗

A single nucleotide polymorphism in glycogen synthase kinase 3-beta promoter gene influences onset of illness in patients affected by bipolar disorder.Semantic proximity Read ↗

Anticipation is not associated with CAG repeat expansion in parent-offspring pairs of patients affected with schizophrenia.Semantic proximity Read ↗

Analysis of CAG/CTG repeat size in Chinese subjects with schizophrenia and bipolar affective disorder using the repeat expansion detection method.Semantic proximity Read ↗

Polyglutamine coding genes in bipolar disorder: lack of association with selected candidate loci.Semantic proximity Read ↗

Prevalence of Huntington's disease gene CAG trinucleotide repeat alleles in patients with bipolar disorder.Semantic proximity Read ↗

CTG18.1 and ERDA-1 CAG/CTG repeat size in bipolar disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.