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Article

Prevalence of Huntington's disease gene CAG trinucleotide repeat alleles in patients with bipolar disorder.

Bipolar disorders - 1 Jun 2015

Ramos Eliana Marisa, Gillis Tammy, Mysore Jayalakshmi S, Lee Jong-Min, Alonso Isabel, Gusella James F, Smoller Jordan W, Sklar Pamela, MacDonald Marcy E, Perlis Roy H

Abstract excerpt

OBJECTIVES: Huntington's disease is a neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms that are caused by huntingtin gene (HTT) CAG trinucleotide repeat alleles of 36 or more units. A greater than expected prevalence of incompletely penetrant HTT CAG repeat alleles observed among individuals diagnosed with major depressive disorder raises the possibility that another mood...

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Source

Open in PubMed Open full text

Identifiers

PMID: 25726852
DOI: 10.1111/bdi.12289
PMCID: PMC9980711

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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