Article
Anticipation in bipolar affective disorder.
American journal of human genetics - 1 Aug 1993
McInnis M G, McMahon F J, Chase G A, Simpson S G, Ross C A, DePaulo J R
Abstract excerpt
Anticipation refers to the increase in disease severity or decrease in age at onset in succeeding generations. This phenomenon, formerly ascribed to observation biases, correlates with the expansion of trinucleotide repeat sequences (TNRs) in some disorders. If present in bipolar affective disord...
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