Analysis of CAG/CTG repeat size in Chinese subjects with schizophrenia and bipolar affective disorder using the repeat expansion detection method.

doi:10.1016/s0006-3223(97)00492-7

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Article

Analysis of CAG/CTG repeat size in Chinese subjects with schizophrenia and bipolar affective disorder using the repeat expansion detection method.

Biological psychiatry - 1 Dec 1998

Li T, Vallada H P, Liu X, Xie T, Tang X, Zhao J, O'Donovan M C, Murray R M, Sham P C, Collier D A

Abstract excerpt

BACKGROUND: Family studies of schizophrenia and bipolar affective disorder provide evidence for genetic anticipation, which (in common with a number of mendelian disorders), may be caused by triplet repeat expansion. This hypothesis is strengthened by evidence from repeat expansion detection (RED...

Topics

Adolescent
Adult
Alleles
Bipolar Disorder
China
Female
Humans
Male
Schizophrenia
Sex Factors
Trinucleotide Repeat Expansion

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