Article
Analysis of CAG/CTG repeat size in Chinese subjects with schizophrenia and bipolar affective disorder using the repeat expansion detection method.
Biological psychiatry - 1 Dec 1998
Li T, Vallada H P, Liu X, Xie T, Tang X, Zhao J, O'Donovan M C, Murray R M, Sham P C, Collier D A
Abstract excerpt
BACKGROUND: Family studies of schizophrenia and bipolar affective disorder provide evidence for genetic anticipation, which (in common with a number of mendelian disorders), may be caused by triplet repeat expansion. This hypothesis is strengthened by evidence from repeat expansion detection (RED) analysis revealing association between the psychoses and long CAG/CTG trinucleotide repeats. METHODS: We performed...
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