Article
Cessation of spermatogenesis in juvenile spermatogonial depletion (jsd/jsd) mice.
International journal of urology : official journal of the Japanese Urological Association - 1 Sept 1997
Kojima Y, Kominami K, Dohmae K, Nonomura N, Miki T, Okuyama A, Nishimune Y, Okabe M
Abstract excerpt
BACKGROUND: Mice homozygous for the jsd (juvenile spermatogonial depletion) allele are sterile because they become azoospermic. The onset of such azoospermia was investigated by histologic analysis of sections of testes from jsd/jsd mice. METHOD: The testes removed from C57BL/6-jsd/jsd mice aged 3 to 10 weeks were examined microscopically. RESULTS: At 3 weeks of age, spermatocytes were seen in most of the...
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