Article
Cryptorchidism rescues spermatogonial differentiation in juvenile spermatogonial depletion (jsd) mice.
Endocrinology - 1 Jan 2004
Shetty Gunapala, Weng Connie C Y
Abstract excerpt
Male mice homozygous for jsd mutation undergo an initial wave of spermatogenesis, but spermatogonial differentiation ceases a few weeks after birth; at that point the tubules show only type A spermatogonia and Sertoli cells. To test whether testicular descent into the scrotum contributes to the block in spermatogonial differentiation, jsd mutant (jsd/jsd) mice were bilaterally cryptorchidized at the age of 4 wk....
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