Article
Spermatogonial differentiation in juvenile spermatogonial depletion (jsd) mice with androgen receptor or follicle-stimulating hormone mutations.
Endocrinology - 1 Jul 2006
Shetty Gunapala, Weng Connie C Y, Porter Karen L, Zhang Zhen, Pakarinen Pirjo, Kumar T Rajendra, Meistrich Marvin L
Abstract excerpt
The jsd mice experience a single wave of spermatogenesis, followed by an arrest of spermatogenesis because of a block in spermatogonial differentiation. Previous pharmacological and surgical studies have indicated that testosterone (T) and low scrotal temperatures but not FSH block spermatogonial differentiation in jsd mice. We sought to test these observations by genetic approaches by producing male jsd mutant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
