Article
Loss of sperm in juvenile spermatogonial depletion (jsd) mutant mice is ascribed to a defect of intratubular environment to support germ cell differentiation.
Journal of cellular physiology - 1 Jan 1992
Mizunuma M, Dohmae K, Tajima Y, Koshimizu U, Watanabe D, Nishimune Y
Abstract excerpt
C57BL/6(B6)-jsd/jsd mice are sterile due to the defective spermatogenesis in the testes. To know the cause of the deficient spermatogenesis in B6-jsd/jsd mice, we examined whether the problem is within or outside the seminiferous tubules by transplanting tubules from cryptorchid testes of B6- +/+ mice into B6-jsd/jsd testes or tubules from B6-jsd/jsd mice into testes of (WB x C57BL/6)F1-W/Wv (hereafter,...
Topics
- Animals
- Cell Differentiation
- Cryptorchidism
- Male
- Mice
- Mice, Inbred C57BL
- Mutation
- Seminiferous Tubules
- Spermatogenesis
- Spermatogonia
- Spermatozoa