Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene expression alterations by conditional knockout of androgen receptor in adult Sertoli cells of Utp14b jsd/jsd (jsd) mice.

Biology of reproduction - 1 Feb 2011

Zhou Wei, Wang Gensheng, Small Christopher L, Liu Zhilin, Weng Connie C, Yang Lizhong, Griswold Michael D, Meistrich Marvin L

Abstract excerpt

Spermatogenesis is dependent primarily on testosterone action on the Sertoli cells, but the molecular mechanisms have not been identified. Attempts to identify testosterone-regulated target genes in Sertoli cells have used microarray analysis of gene expression in mice lacking the androgen receptor (AR) in Sertoli cells (SCARKO) and wild-type mice, but the analyses have been complicated both by alteration of germ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DEAD-box RNA Helicases
Share to Microarray Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Androgen

Share to Ribonucleoproteins, Small Nucleolar

Share to Sertoli Cells

Share to Spermatocytes

Share to Spermatogonia

Share to Testis

Source

Open in PubMed Open full text

Identifiers

PMID: 21312389
DOI: 10.1095/biolreprod.110.090530
PMCID: PMC3071269

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene expression alterations by conditional knockout of androgen receptor in adult Sertoli cells of Utp14b jsd/jsd (jsd) mice.PMID 21312389Read ↗

Gene expression alterations by conditional knockout of androgen receptor in adult sertoli cells of Utp14b(jsd/jsd) (jsd) mice.Semantic proximity Read ↗

The Effect of a Sertoli Cell-Selective Knockout of the Androgen Receptor on Testicular Gene Expression in Prepubertal MiceSemantic proximity Read ↗

Early effects of Sertoli cell‐selective androgen receptor ablation on testicular gene expressionSemantic proximity Read ↗

Genome-wide identification of AR-regulated genes translated in Sertoli cells in vivo using the RiboTag approach.Semantic proximity Read ↗

Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal miceSemantic proximity Read ↗

Single-Cell RNA Sequencing Defines the Regulation of Spermatogenesis by Sertoli-Cell Androgen SignalingSemantic proximity Read ↗

Identification of Sertoli cell-specific transcripts in the mouse testis and the role of FSH and androgen in the control of Sertoli cell activitySemantic proximity Read ↗

Identification of testosterone-/androgen receptor-regulated genes in mouse Sertoli cellsSemantic proximity Read ↗

New Candidate Genes Identified for Controlling Mouse Gonadal Sex Determination and the Early Stages of Granulosa and Sertoli Cell Differentiation1Semantic proximity Read ↗

Temporal Role of Sertoli Cell Androgen Receptor Expression in Spermatogenic DevelopmentSemantic proximity Read ↗

CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in miceSemantic proximity Read ↗

Transcriptional profiling of androgen receptor (AR) mutants suggests instructive and permissive roles of AR signaling in germ cell development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.