Article
Genetic factors contributing to defective spermatogonial differentiation in juvenile spermatogonial depletion (Utp14bjsd) mice.
Biology of reproduction - 1 Aug 2007
Bolden-Tiller Olga U, Chiarini-Garcia Helio, Poirier Christophe, Alves-Freitas Daniel, Weng Connie C, Shetty Gunapala, Meistrich Marvin L
Abstract excerpt
Male mice that are homozygous for the juvenile spermatogonial depletion (jsd) mutation in the Utp14b gene undergo several waves of spermatogenesis. However, spermatogonial differentiation ceases and in adults, spermatogonia are the only germ cells that remain. To understand further the blockage in spermatogonial differentiation in Utp14b(jsd) mutant mice, we correlated the rate and severity of spermatogonial...
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