Article
PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 1998
Risinger J I, Hayes K, Maxwell G L, Carney M E, Dodge R K, Barrett J C, Berchuck A
Abstract excerpt
Mutation of the PTEN tumor suppressor gene is a frequent event in endometrial cancers. In other types of cancers, PTEN mutation has been associated with metastatic behavior and advanced stage. To examine the relationship between PTEN mutation and clinical features of endometrial cancers, we screened 136 cases for mutations in the nine exons and intronic splice sites of the PTEN gene, using single-strand...
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