Article
Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jan 2014
McConechy Melissa K, Ding Jiarui, Senz Janine, Yang Winnie, Melnyk Nataliya, Tone Alicia A, Prentice Leah M, Wiegand Kimberly C, McAlpine Jessica N, Shah Sohrab P, Lee Cheng-Han, Goodfellow Paul J, Gilks C Blake, Huntsman David G
Abstract excerpt
Ovarian endometrioid carcinomas and endometrial endometrioid carcinomas share many histological and molecular alterations. These similarities are likely due to a common endometrial epithelial precursor cell of origin, with most ovarian endometrioid carcinomas arising from endometriosis. To directly compare the mutation profiles of two morphologically similar tumor types, endometrial endometrioid carcinomas...
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