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Article

PTEN mutations as predictive marker for the high-grade endometrial cancer development in slovak women.

Physiological research - 27 Dec 2022

Gbelcová H, Gergely L, Šišovský V, Straka Ľ, Böhmer D, Pastoráková A, Sušienková K, Repiská V, Korbeľ M, Danihel Ľ, Priščáková P

Abstract excerpt

Endometrial carcinoma (ECa) is one of the most common neoplasia of the female genital tract. The phosphatase and tensin (PTEN) homolog is the most frequently mutated tumor suppressor gene in endometrial carcinoma. PTEN encodes a phosphatase, a key regulatory enzyme involved in a signal transduction pathway that regulates cell growth, migration and apoptosis. The study evaluates an association between the...

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Identifiers

PMID: 36592448
PMCID: PMC9854001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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