Article
Human sulfotransferase SULT1C1 pharmacogenetics: gene resequencing and functional genomic studies.
Pharmacogenetics - 1 Dec 2001
Freimuth R R, Eckloff B, Wieben E D, Weinshilboum R M
Abstract excerpt
Sulfotransferase (SULT) enzymes catalyze an important phase II reaction in the biotransformation of many drugs and other xenobiotics. We previously cloned the human SULT1C1 cDNA and gene as steps toward pharmacogenetic studies. We have now 'resequenced' the exons, portions of introns flanking exons and approximately 315 bp of the 5' flanking region of SULT1C1 in 89 DNA samples from Caucasian subjects to identify...
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