Article
Coordinate control and variation in X-linked gene expression among female mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1997
Greenwood A D, Southard-Smith E M, Galecki A T, Burke D T
Abstract excerpt
In normal female mammals, one of the two X Chromosome (Chr) homologs per cell is silenced coordinately during early embryogenesis. The genes located on the inactivated X homolog are predicted to be influenced by the same underlying repression mechanism. To test the uniformity of cis-acting gene repression, 32 genetically identical F1 female mice were analyzed for differential expression of homologous alleles at...
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